| Autor: |
Wiebke Halpape, Donat Wulf, Bart Verwaaijen, Anna Sophie Stasche, Sanja Zenker, Janik Sielemann, Sebastian Tschikin, Prisca Viehöver, Manuel Sommer, Andreas P. M. Weber, Carolin Delker, Marion Eisenhut, Andrea Bräutigam |
| Rok vydání: |
2023 |
| Popis: |
Photosynthesis by which plants convert carbon dioxide to sugars using the energy of light is fundamental to life as it forms the basis of nearly all food chains. Surprisingly, our knowledge about its transcriptional regulation remains incomplete. Effort for its agricultural optimization have mostly focused on post-translational regulatory processes1–3but photosynthesis is regulated at the post-transcriptional4and the transcriptional level5. Stacked transcription factor mutations remain photosynthetically active5,6and additional transcription factors have been difficult to identify possibly due to redundancy6or lethality. Using a random forest decision tree-based machine learning approach for gene regulatory network calculation7we determined ranked candidate transcription factors and validated five out of five tested transcription factors as controlling photosynthesisin vivo. The detailed analyses of previously published and newly identified transcription factors suggest that photosynthesis is transcriptionally regulated in a partitioned, non-hierarchical, interlooped network. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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