Initiation and adherence to isoniazid preventive therapy in children under 5 years of age in Manhiça, Southern Mozambique

Autor: Agnès Montoya i de Manuel-Rimbau, Dinis Nguenha, Edson Mambuque, Joanna Ehrlich, Shilzia Munguambe, Belén Saavedra, Teodimiro Matsena, Hélio Chiconela, Aina Casellas, Elisa López-Varela, Sozinho Acacio, Alberto L Garcia-Basteiro
Rok vydání: 2022
Předmět:
Zdroj: Journal of Tropical Pediatrics. 69
ISSN: 1465-3664
0142-6338
DOI: 10.1093/tropej/fmad009
Popis: The WHO recommends preventive treatment for all pediatric contacts of a confirmed TB case, but coverage remains low in many high TB burden countries. We aimed to assess the coverage and adherence of the isoniazid preventive therapy (IPT) program among children under 5 years of age with household exposure to an adult pulmonary TB case in a rural district of Southern Mozambique. The estimated IPT coverage was 11.7%. A longer distance to the health center and lower age of the children hindered IPT initiation. Among patients who started IPT, 12/18 (69.9%) were adherent to the 6-month treatment.
Databáze: OpenAIRE