Efficacy of lysine versus mupirocin in the treatment of non-diabetic foot ulcer: the sessing scale for assessment of pressure ulcer
| Autor: | B Sandeep, Shashi Kumara, Vani J, Y P Sridhar Prasad, Prathima C |
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| Rok vydání: | 2020 |
| Předmět: | |
| Zdroj: | International Journal of Basic & Clinical Pharmacology. 10:18 |
| ISSN: | 2279-0780 2319-2003 |
| DOI: | 10.18203/2319-2003.ijbcp20205449 |
| Popis: | Background: This present studies intended to evaluate the wound healing ability, efficacy and tolerability of lysine cream (15%) in non- diabetic foot ulcer assessed by way of sessing scale.Methods: A randomized, open-label, interventional study was directed on 20 subjects (participants) non-diabetic ulcers. Participants were grouped into two groups, control (n=10) and case (n=10). The control was treated with standard treatment with mupirocin and the test group was treated with standard treatment alongside lysine cream (15%) twice every day. Wound healing in the participants was assessed by the sessing scales.Results: A total of 20 participants were allotted into two groups. The results expressed as mean±standard deviation values imply the size and depth of the foot ulcer from the first week to the 8th week. Both the groups showed a significant increase the ulcer healing and decrease the pressure of foot ulcer of over a period of 8 weeks. Assessment of the first week showed no significant ulcer healing and its pressure. The overall outcome indicated that the lysine-treated group extensively reduced each of the parameters favouring wound healing than the standard therapy with mupirocin (control group).Conclusions: Results concluded that, lysine cream is better efficacious in the repair of wound and additionally well tolerated compared to mupirocin. |
| Databáze: | OpenAIRE |
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