Green synthesis of in situ forming alginate-urethane hydrogel through Schiff base reaction
| Autor: | Maryam Sahraro, Mehdi Barikani, Atefeh Torabi, Hamed Daemi |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
In situ
Schiff base Materials science Biocompatibility Hydrogen bond Mechanical Engineering 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics 01 natural sciences 0104 chemical sciences chemistry.chemical_compound chemistry Chemical engineering Mechanics of Materials Self-healing hydrogels General Materials Science Thermal stability Fourier transform infrared spectroscopy 0210 nano-technology Derivative (chemistry) |
| Zdroj: | Materials Letters. 254:194-197 |
| ISSN: | 0167-577X |
| DOI: | 10.1016/j.matlet.2019.07.052 |
| Popis: | Despite recent advances in preparing hydrogels, their application is mainly limited due to the poor mechanical properties or the high risk of inflammatory response. Therefore, in this study a fully defined in situ hydrogelation system is developed based on green-chemistry in which alginate dialdehyde (ADA) was coupled to an isocyanate-free urethane derivative. FTIR analysis along with 1HNMR confirmed hydrogel formation. Improved thermal stability of the hydrogel was an indication of hydrogen bonding at various sites. The microgels possessed the mean diameter of 4 microns, reasonable gelation time and suitable biocompatibility which made them prospective candidates for various fields of biomedicine. |
| Databáze: | OpenAIRE |
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