Bioactive Palladium Azomethine Chelates, a Review of Recent Research

Autor:	Amr Nassar, Prof. LOUTFY MADKOUR
Rok vydání:	2016
Předmět:	inorganic chemicals Antifungal 010405 organic chemistry medicine.drug_class chemistry.chemical_element 010402 general chemistry Antimicrobial 01 natural sciences 0104 chemical sciences Inorganic Chemistry chemistry Biological property medicine Structure–activity relationship Organic chemistry Chelation Physical and Theoretical Chemistry Palladium Biological evaluation
Zdroj:	Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry. 46:1349-1366
ISSN:	1553-3182 1553-3174
DOI:	10.1080/15533174.2015.1004463
Popis:	Pd(II) complexes of various donor atom ligands posses antitumor and antiviral, -malarial, -fungal, and -microbial activities. This review article deals with the structure activity relationship for a variety of palladium azomethine complexes in biomedical applications. Moreover, the types of different biological evaluation (antitumor, antibacterial, and antifungal) activities will vary considerably from one country to another. This study gives an up-to-date overview of the palladium azomethine complexes with an emphasis on the new strategies used in the development of new antimicrobial and antitumor agents. Therefore, the use of palladium azomethine complexes in medicinal chemistry is interesting as potential application in the biological properties with less toxic drugs compounds. The results in this review show that the use of Pd(II) azomethine complexes in medicine may always be promising and encourage further studies in the field.
Databáze:	OpenAIRE
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