Synthesis of bifluorenes via cobalt halide radical coupling

Autor:	Christopher A. Bradley, Tiffany A. Huang, Fernando Hung-Low, Malik H. Al-Afyouni
Rok vydání:	2011
Předmět:	chemistry.chemical_classification Reaction mechanism Organic Chemistry Halide chemistry.chemical_element Photochemistry Biochemistry Transition metal chemistry Polymerization Drug Discovery Polymer chemistry Lithium Bimetallic strip Cobalt Alkyl
Zdroj:	Tetrahedron Letters. 52:3261-3265
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2011.03.127
Popis:	Reaction of in situ generated lithium fluorenide salts with cobalt chloride results in formation of the corresponding bifluorenes. The scope of fluorenes that can be coupled include those containing substituents amenable to polymerization for application to poly(bifluorene) synthesis and alkyl substituted fluorenes for use in the preparation of bimetallic transition metal complexes. Based on experiments using a radical trap, the reaction mechanism involves reduction of cobalt and subsequent fluorenyl radical coupling. Overall, this study demonstrates a simple and effective method for preparation of hindered tertiary and quaternary C–C bonds using a readily available and inexpensive coupling agent.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d83eea7f3f0184fc236f97a42aff280d https://doi.org/10.1016/j.tetlet.2011.03.127 Zobrazit plný text záznamu Full Text from ScienceDirect