Immune System Modulation with LOFU And HIFU Treatment of Prostate Cancer

Autor:	C. Guha, Z. Huagang, W. Chen, R. Carlosn, N. T. Sanghvi, Yoichiro Matsumoto, Lawrence A. Crum, Gail Reinette ter Haar
Rok vydání:	2011
Předmět:	Systemic disease Pathology medicine.medical_specialty business.industry medicine.medical_treatment medicine.disease High-intensity focused ultrasound Radiation therapy Prostate cancer Coagulative necrosis Immune system Hifu treatment Medicine Viability assay business
Zdroj:	AIP Conference Proceedings.
ISSN:	0094-243X
DOI:	10.1063/1.3607918
Popis:	High intensity focused ultrasound (HIFU) results in instantaneous coagulative tissue necrosis. In contrast, “low” energy focused ultrasound (LOFU) induces membrane perturbation while maintaining cell viability. This report explores the tumor immunomodulatory roles of LOFU and HIFU combination treatment. We hypothesized that administration of repeated cycles of LOFU, followed by HIFU would release tumor‐derived peptide‐heat shock protein complexes in the blood and induce systemic tumor‐specific immune response that would enhance tumor control of both local and systemic disease.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d7c5b52a4d27d312180dfa6b3686d053 https://doi.org/10.1063/1.3607918 Zobrazit plný text záznamu