High-Performance Liquid Chromatographic Determination of Praziquantel in Plasma and Tissues of Cultured Fish for Residue and Pharmacokinetic Studies

Autor:	V. Hormazabal, M. Yndestad
Rok vydání:	1995
Předmět:	Residue (complex analysis) Chromatography Plasma High-performance liquid chromatography Praziquantel chemistry.chemical_compound Pharmacokinetics chemistry Blood plasma Acetone medicine Molecular Medicine Fish medicine.drug
Zdroj:	Journal of Liquid Chromatography. 18:589-597
ISSN:	0148-3919
DOI:	10.1080/10826079508009259
Popis:	A simple method for the determination of praziquantel in fish plasma and tissues by HPLC is presented. The samples were extracted with acetone, the organic layer then being separated with diethylether-hexane and evaporated to dryness. The lower limit of quantification was 5, 15, and 20 μg/kg, for muscle, liver, and plasma, respectively.
Databáze:	OpenAIRE
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