Treatment of acute rhinosinusitis diagnosed by clinical criteria or ultrasound in primary care
| Autor: | Ilkka Kunnamo, Matti Revonta, Helena Varonen, Jarkko Ruotsalainen, Henrik Malmberg, Seppo Savolainen, Marjukka Mäkelä |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
medicine.medical_specialty
business.industry Ultrasound Public Health Environmental and Occupational Health Primary care Amoxicillin medicine.disease Placebo 3. Good health law.invention Surgery 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Clinical diagnosis Internal medicine Acute rhinosinusitis Medicine 030212 general & internal medicine 030223 otorhinolaryngology business Sinusitis medicine.drug |
| Zdroj: | Scandinavian Journal of Primary Health Care. 21:121-126 |
| ISSN: | 1502-7724 0281-3432 |
| Popis: | Scand J Prim Health Care 2003;21:00-00. ISSN 0281-34323 Objectives r - r To compare antibiotics and placebo in patients with clinically diagnosed acute maxillary sinusitis (AMS). To study whether sinus ultrasound examination would help to detect those patients who benefit from antibiotic therapy. Design r - r A double-blind, randomised, placebo-controlled multicentre trial. Setting r - r Nine primary care sites in Finland. Subjects r - r 150 adult patients (mean age 39.7 years) with a clinical diagnosis of sinusitis. Intervention r - r Antibiotics (amoxicillin 750 mg 2 2, doxycycline 100 mg 2 2 or penicillin V 1500 mg 2 2) or placebo twice daily for 7 days; all patients were examined with sinus ultrasound after randomisation. Main outcome measure r - r Clinical success (patients' report of recovery) in telephone interview at 2 weeks. Results r - r A total of 146 patients completed the 2-week follow-up. Patients receiving antibiotics achieved... |
| Databáze: | OpenAIRE |
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