P126 - Observed vs. predicted effects of protein binding: Improving in vivo predictions of hepatic clearance, intracellular concentration and IC50 values

Autor:	Robert L. St. Claire, Jonathan P. Jackson, Kenneth R. Brouwer, Ronald Laethem
Rok vydání:	2020
Předmět:	Pharmacology Chemistry In vivo Biophysics Ic50 values Pharmaceutical Science Hepatic clearance Pharmacology (medical) Plasma protein binding Intracellular
Zdroj:	Drug Metabolism and Pharmacokinetics. 35:S60-S61
ISSN:	1347-4367
DOI:	10.1016/j.dmpk.2020.04.127
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d63bb1d5c20a5b47d785181cb4d48a23 https://doi.org/10.1016/j.dmpk.2020.04.127 Zobrazit plný text záznamu Full Text from ScienceDirect