Evidence of ongoing virus multiplication in type B fulminant hepatitis

Autor:	Subrat K. Acharya, Tandon Bn, B.M. Gandhi, Mohammad Irshad, Yogendra Kumar Joshi
Rok vydání:	1988
Předmět:	Hepatitis B virus Hepatitis b e antigen Hepatology business.industry Gastroenterology virus diseases Virus multiplication Hepatitis B medicine.disease_cause medicine.disease Virology digestive system diseases HBeAg Immunology medicine business Fulminant hepatitis Hepatic encephalopathy
Zdroj:	Journal of Gastroenterology and Hepatology. 3:139-142
ISSN:	1440-1746 0815-9319
DOI:	10.1111/j.1440-1746.1988.tb00229.x
Popis:	The presence of HBeAg- and HBV-specific DNA-polymerase (DNA-P) activity-regarded as markers of HBV multiplication-were studied in 40 patients with fulminant hepatitis B within 1-5 days of the onset of hepatic encephalopathy. HBeAg and DNA-P were detected in three (7 %) and 21 (51%) of the patients respectively. Only three (7%) were positive for anti-HBs. DNA-P activity was present in 38.1 % even 10 days after the appearance of icterus. Present findings confirm an ongoing HBV multiplication in about half of the patients of fulminant hepatitis B.
Databáze:	OpenAIRE
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