Adherence to guideline excision margins in head and neck melanoma: the influence on 5-year survival and loco-regional recurrence

Autor:	Michael Senior, Elisabeth Zetlitz, Gregory A. J. Robertson, Taimur Shoaib, Bernard F. Robertson
Rok vydání:	2011
Předmět:	Univariate analysis medicine.medical_specialty business.industry Wide local excision medicine.medical_treatment Melanoma medicine.disease Surgery Breslow Thickness medicine.anatomical_structure Scalp Cutaneous melanoma medicine T-stage business Survival rate
Zdroj:	European Journal of Plastic Surgery. 35:507-515
ISSN:	1435-0130 0930-343X
Popis:	Guidelines for the management of cutaneous melanoma suggest wide local excision of increasing margins for increasing Breslow thickness of the primary neoplasm. These guidelines are based on randomized controlled trial data from limb and trunk melanoma studies. We performed retrospective analysis of our institution's head and neck melanoma database to investigate the effect of narrow excision margins on survival and loco-regional recurrence. We identified 101 patients with node-negative head and neck melanoma from 1993 to 2001 who had prospectively gathered data. The overall 5-year loco-regional recurrence rate (LR) was 37%. The overall 5-year melanoma-specific survival rate (5y.s.) was 70%. When guidelines were followed (n = 36), LR was 19% and 5y.s. was 89%. When guidelines were not followed (n = 65), LR was 46% and 5y.s. was 60%. On univariate analysis, we found scalp location (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d2c052ef95519f142a577535f3a6af6e https://doi.org/10.1007/s00238-011-0668-9 Zobrazit plný text záznamu Full text from SpringerLink