Five new alkaloids from Aconitum apetalum (Ranunculaceae)
| Autor: | Yan-Rong Zeng, Yu Zhang, Zhan-Xing Hu, Xiao-Jiang Hao, Hong-Yu Tang, Haji Aker Aisa, Xiao-Hui Yan |
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| Rok vydání: | 2019 |
| Předmět: |
Aconitum apetalum
Mosaic virus biology 010405 organic chemistry Chemistry Stereochemistry Alkaloid Ranunculaceae Plant Science Antimicrobial biology.organism_classification 01 natural sciences Biochemistry Terpenoid 0104 chemical sciences 010404 medicinal & biomolecular chemistry Aporphine alkaloids Agronomy and Crop Science Biotechnology |
| Zdroj: | Phytochemistry Letters. 29:6-11 |
| ISSN: | 1874-3900 |
| DOI: | 10.1016/j.phytol.2018.10.017 |
| Popis: | Twenty-one alkaloids, including five new ones, acoapetaldines A-E (1-5), were isolated from the whole plants of Aconitum apetalum. Among them, 1 is an aconitine-type diterpenoid alkaloid, 2 and 3 are aporphine alkaloids and 4 and 5 are napelline-type diterpenoid alkaloids. The structures of the new alkaloids were elucidated by spectroscopic data analysis and that of acoapetaldine D (4) was confirmed by single crystal X-ray crystallography. Acoapetaldine A (1) and aconorine (12) exhibited moderate anti-tobacco mosaic virus (anti-TMV) activity, while corydine (15) displayed moderate antimicrobial activity against Pseudomonas aeruginosa. |
| Databáze: | OpenAIRE |
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