Mobile genetic elements and pathogenicity islands encoding bacterial toxins

Autor:	Sarah Tjaden, Jörg Hacker, Ulrich Dobrindt, Sadrick Shah
Rok vydání:	2015
Předmět:	Bacteriophage Genetics Plasmid biology Horizontal gene transfer Nonsense mutation Mobile genetic elements biology.organism_classification Pathogenicity island Gene Loss function
DOI:	10.1016/b978-0-12-800188-2.00002-1
Popis:	Evolution of pathogenic bacteria results from the acquisition of mobile genetic elements. Furthermore, loss of genetic information by deletion and the acquisition of nonsense mutations also contribute to genetic diversification. Mobile or mobilizable genetic elements encoding bacterial protein toxins promote horizontal gene transfer of toxin determinants. The genetic organization of mobile genetic elements carrying bacterial protein toxin genes mirrors the importance of recombination, gene acquisition- and loss of function events for continuous evolution and the generation of new protein toxin variants.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d21660dc0486df28661e67fc58a4fd20 https://doi.org/10.1016/b978-0-12-800188-2.00002-1 Zobrazit plný text záznamu