Parkinsonism: differential age-trend in Helicobacter pylori antibody
Autor: | RJ Dobbs, Dale W. Peterson, Andre Charlett, C. Weller, Sylvia M. Dobbs |
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Rok vydání: | 2000 |
Předmět: |
medicine.medical_specialty
Hepatology biology business.industry Parkinsonism Dopaminergic Gastroenterology Case-control study Odds ratio Helicobacter pylori medicine.disease biology.organism_classification Serology Central nervous system disease Interquartile range Internal medicine Immunology medicine Pharmacology (medical) business |
Zdroj: | Alimentary Pharmacology & Therapeutics. 14:1199-1205 |
ISSN: | 0269-2813 |
DOI: | 10.1046/j.1365-2036.2000.00815.x |
Popis: | Background: Parkinsonism is associated with prodromal peptic ulceration. Dopamine antagonists provoke experimental ulcer, dopaminergic agents protect, and might inhibit growth of Helicobacter pylori. Objective: To describe the relationship between H. pylori serology and parkinsonism. Methods: Serum H. pylori anti-urease-IgG antibody was measured in 105 people with (idiopathic) parkinsonism, 210 without, from same locality. None had received specific eradication therapy. Results: Controls showed a birth-cohort effect: antibody titre rose from 30 to 90 years (P |
Databáze: | OpenAIRE |
Externí odkaz: | |
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