Parkinsonism: differential age-trend in Helicobacter pylori antibody

Autor: RJ Dobbs, Dale W. Peterson, Andre Charlett, C. Weller, Sylvia M. Dobbs
Rok vydání: 2000
Předmět:
Zdroj: Alimentary Pharmacology & Therapeutics. 14:1199-1205
ISSN: 0269-2813
DOI: 10.1046/j.1365-2036.2000.00815.x
Popis: Background: Parkinsonism is associated with prodromal peptic ulceration. Dopamine antagonists provoke experimental ulcer, dopaminergic agents protect, and might inhibit growth of Helicobacter pylori. Objective: To describe the relationship between H. pylori serology and parkinsonism. Methods: Serum H. pylori anti-urease-IgG antibody was measured in 105 people with (idiopathic) parkinsonism, 210 without, from same locality. None had received specific eradication therapy. Results: Controls showed a birth-cohort effect: antibody titre rose from 30 to 90 years (P
Databáze: OpenAIRE
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