Gecko-inspired chitosan adhesive for tissue repair

Autor: Antonio Lauto, Damia Mawad, Rhiannon P. Kuchel, Michael J. Higgins, James M. Hook, Simon J. Myers, Herleen Ruprai, Richard D. Tilley, Samuel J Frost
Rok vydání: 2016
Předmět:
Zdroj: NPG Asia Materials. 8:e280-e280
ISSN: 1884-4057
1884-4049
DOI: 10.1038/am.2016.73
Popis: This study describes a simple one-step fabrication process of a chitosan film that has nanoscale pillars. The adhesive is laser-bonded to tissue and does not require pillar coating to enhance bonding in water. In comparison with a ‘flat’ adhesive without pillars, the nanostructured adhesive bonded significantly stronger to tissue under either stress or pressure. This adhesive combines two mechanisms for tissue bonding: one based on the nanopatterned surface that increases the adhesion strength over short distances (van der Waals and electrostatic interactions) and another based on elastic interaction with polymer chains over much longer distances.
Databáze: OpenAIRE