| Autor: |
Hanene Lassoued Ferjani, Safa Rahmouni, Dorra Ben Nessib, Wafa Triki, Kaouther Maatallah, Dhia Kaffel, Wafa Hamdi |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Acta Orthopaedica Belgica. 88:655-660 |
| ISSN: |
0001-6462 |
| DOI: |
10.52628/88.4.10839 |
| Popis: |
Sarcoidosis is a systemic inflammatory granulomatous disease that can develop in almost any organ system. Rheumatologists may encounter sarcoidosis in different situations varying from arthralgia to bone involvement. While the peripheral skeleton was a frequent location, data regarding axial involvement is scarce. Most patients with vertebral involvement have a known diagnosis of intrathoracic sarcoidosis. They tend to report mechanical pain or tenderness over the involved area. Imaging modalities, particularly Magnetic Resonance Imaging (MRI), are a mainstay of axial screening. It helps exclude differential diagnoses and delineate the extent of bone involvement. Histological confirmation combined with the ap- propriate clinical and radiological presentation is the key of diagnosis. Corticosteroids remain the cornerstone of treatment. In refractory cases, methotrexate is the steroid- sparing agent of choice. Biologic therapies may be used, although the evidence base for their efficacy is bone sarcoidosis controversial. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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