Massive Perivillous Fibrin Deposition in Congenital Cytomegalovirus Infection: A Case Report
| Autor: | Sanjita Ravishankar, Yi Yuan Zhou, Catherine K Gestrich |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pathology
medicine.medical_specialty Stromal cell business.industry Placental Finding Fibrin deposition Congenital cytomegalovirus infection General Medicine medicine.disease Pathology and Forensic Medicine medicine.anatomical_structure Hemosiderin Placenta Pediatrics Perinatology and Child Health Chronic Villitis Medicine business |
| Zdroj: | Pediatric and Developmental Pathology. 24:47-50 |
| ISSN: | 1615-5742 1093-5266 |
| DOI: | 10.1177/1093526620961352 |
| Popis: | Cytomegalovirus (CMV) infection is one of the most common congenital viral infections. Classically associated placental findings include chronic villitis with plasma cells, stromal hemosiderin deposition, and identification of viral inclusions in villous endothelial and stromal cells. We present a case of confirmed congenital CMV infection that lacked these classical findings, but demonstrated massive perivillous fibrin deposition (MPVFD). This is the first report of CMV associated with MPVFD. MPVFD is an uncommon placental lesion associated with adverse fetal outcomes and a high risk of recurrence. However, the recurrence risk in patients with an infectious cause may be lower in than patients with other associated clinical conditions. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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