ChemInform Abstract: Thieno[2,3-d]pyrimidines and -[1,3]oxazines as Glutamate Antagonists and Investigations on the Inhibitory Potency Toward Human Leukocyte Elastase

Autor:	Camino M. González Tanarro, Detlef Briel, Klaus Unverferth, Michael Guetschow, A. Rybak, Christiane Kronbach
Rok vydání:	2010
Předmět:	chemistry.chemical_classification Inhibitory potency chemistry Stereochemistry Antagonist Kainate receptor Oxazines General Medicine Thiophene derivatives Glutamate antagonists Human Leukocyte Elastase
Zdroj:	ChemInform. 41
ISSN:	0931-7597
DOI:	10.1002/chin.201044166
Popis:	Fused thiophene derivatives such as thienopyrimidines, thienooxazines, and thienothiazines with the common 5-methyl-6-phenyl substitution pattern are designed and synthesized as cyclic analogues of a particularly active antagonist at the GluR6 kainate receptor.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d09a9c7a9d875ac8a13eace1afb81bcb https://doi.org/10.1002/chin.201044166 Zobrazit plný text záznamu Plný text