Rezidivierende Thrombose der Vena subclavia während Östrogentherapie eines Prostatakarzinoms*

Autor:	Fischer H, Wambach G
Rok vydání:	2008
Předmět:	Prothrombin time Clotting factor medicine.medical_specialty medicine.diagnostic_test business.industry medicine.medical_treatment Cancer General Medicine medicine.disease Thrombosis Cardiac pacemaker Surgery medicine.anatomical_structure Prostate medicine Carcinoma business Subclavian vein
Zdroj:	DMW - Deutsche Medizinische Wochenschrift. 109:1725-1727
ISSN:	1439-4413 0012-0472
DOI:	10.1055/s-2008-1069443
Popis:	A cardiac pacemaker had been implanted in a patient with carcinoma of the prostate because of a sick sinus node. Thrombosis of the left subclavian vein occurred four weeks later. After complete recanalisation following thrombolytic treatment a recurrence of the thrombosis occurred during high-dosage intravenous oestrogen treatment. Continuous increase of prothrombin time was observed during oestrogen administration while the oral anticoagulation had remained unaltered. This indicated increase of synthesis of vitamin-K-dependent clotting factors by the oestrogens. This case demonstrates that in patients with implanted material and oral long-term anticoagulation the indication for oestrogen treatment must be extremely accurately. In every case very close surveillance of coagulation is necessary.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::d06eb5bccd9453d0d9b9e8382ed430cd https://doi.org/10.1055/s-2008-1069443 Zobrazit plný text záznamu