Vogt–Koyanagi–Harada syndrome – current perspectives
Autor: | Abeir Baltmr, Susan Lightman, Oren Tomkins-Netzer |
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Rok vydání: | 2016 |
Předmět: |
Autoimmune disease
medicine.medical_specialty business.industry Panuveitis Disease progression Disease medicine.disease Dermatology eye diseases Serous Retinal Detachment Surgery 03 medical and health sciences Ophthalmology Serous fluid 0302 clinical medicine 030221 ophthalmology & optometry medicine Treatment strategy Vogt-Koyanagi-Harada syndrome business 030217 neurology & neurosurgery |
Zdroj: | Clinical Ophthalmology. 10:2345-2361 |
ISSN: | 1177-5483 |
DOI: | 10.2147/opth.s94866 |
Popis: | Vogt-Koyanagi-Harada syndrome is a cause of noninfectious panuveitis, leading to significant vision loss in many patients. It is an autoimmune disease occurring in genetically susceptible individuals and clinically presents as bilateral panuveitis with serous retinal detachments and hyperemic, swollen optic discs, which are associated with neurological and auditory manifestations. Early diagnosis and prompt and adequate treatment with immunosuppressive agents (corticosteroids and other immunosuppressive drugs) may halt disease progression and prevent recurrences and vision loss. This review summarizes the current knowledge on the variable clinical aspects of this disease, highlighting diagnostic and treatment strategies. |
Databáze: | OpenAIRE |
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