Menopause is associated with the stiffness of the common carotid artery in 50-year-old women
| Autor: | Bengt Vessby, Tommy Jonason, Toomas Kangro, Egil Henriksen, Ivar Ringqvist |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
medicine.medical_specialty
Multivariate analysis Physiology business.industry Arteriosclerosis medicine.disease Menopause Endocrinology Blood pressure medicine.anatomical_structure Internal medicine medicine.artery Circulatory system medicine Cardiology Common carotid artery business Blood vessel Artery |
| Zdroj: | Clinical Physiology. 18:149-155 |
| ISSN: | 0144-5979 |
| DOI: | 10.1046/j.1365-2281.1998.00088.x |
| Popis: | To determine if menopause has an effect on the elasticity of the arteries, the stiffness index of the common carotid artery was studied in 84 premenopausal and 139 post-menopausal women. The study group was age-homogeneous, all women being 50 years of age. There were no significant differences between pre- and post-menopausal women regarding atherosclerosis, when measured as the number of subjects with plaques or intimal-medial thickness. The diameter of the common carotid artery was significantly larger in post-menopausal women. The diameter was correlated to measurements of body size which did not, however, differ between the two groups. The mean stiffness indexes were 4.99 +/- 1.02 and 5.38 +/- 1.21 in the pre- and post-menopausal groups respectively (P < 0.05). In a multivariate analysis, menopause (P < 0.05), and also serum insulin levels (P < 0.01) and smoking (P < 0.05) were found to have independent significant associations to the stiffness index. In conclusion, menopause is associated with reduced elasticity of the carotid arteries in 50-year-old women. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text