Outcomes From Re-Treatment and Cerebrospinal Fluid Analyses in Patients With Syphilis Who Had Serological Nonresponse or Lack of Seroreversion After Initial Therapy
| Autor: | Andrea Shahum, Xiaohui Zhang, Jane S Chen, Bin Yang, Ligang Yang, Justin D. Radolf, Yaohua Xue, Arlene C. Seña, Heping Zheng, Liuyuan Wang |
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| Rok vydání: | 2020 |
| Předmět: |
Microbiology (medical)
Sexually transmitted disease medicine.medical_specialty 030505 public health business.industry Medical record Public Health Environmental and Occupational Health Antibody titer Dermatology medicine.disease Serology Neurosyphilis 03 medical and health sciences Syphilis Serodiagnosis 0302 clinical medicine Infectious Diseases Internal medicine Medicine Syphilis 030212 general & internal medicine Seroconversion 0305 other medical science business |
| Zdroj: | Sexually Transmitted Diseases. 48:443-450 |
| ISSN: | 1537-4521 0148-5717 |
| DOI: | 10.1097/olq.0000000000001321 |
| Popis: | BACKGROUND We conducted an observational study to determine whether patients with syphilis who do not demonstrate serological cure or lack of seroreversion in nontreponemal (NT) antibody titers after initial therapy benefit from re-treatment and cerebrospinal fluid (CSF) analysis. METHODS We enrolled patients with syphilis from sexually transmitted disease clinics in Guangzhou, China, who had persistent NT titers after therapy. Serological nonresponse was defined as a |
| Databáze: | OpenAIRE |
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