Rationalized preoperative management of hip and knee arthroplasty patients: A retrospective cohort study

Autor: Thomas Prasloski, Jack Huang, Jacqueline D. Trudeau, Garrett Barry, John K. Peel, Bassam A. Masri, Lawrence Sham
Rok vydání: 2021
Předmět:
Zdroj: Perioperative Care and Operating Room Management. 24:100177
ISSN: 2405-6030
DOI: 10.1016/j.pcorm.2021.100177
Popis: Background Current practices prioritize transfusion readiness over preoperative hemoglobin (Hgb) optimization in elective arthroplasty patients. We characterized the relationship between preoperative Hgb and perioperative transfusion among patients undergoing primary hip and knee replacement in order to identify a threshold Hgb at which the probability of transfusion is negligibly low. We then evaluated an alternative preoperative patient management algorithm using an evidence-guided threshold for pre-transfusion testing. Methods We performed a retrospective cohort study of adults undergoing elective primary hip or knee arthroplasty at two academic hospitals between 2010 and 2017. A subset of patients received either no treatment, iron supplementation, or erythropoietin preoperatively. Logistic regressions modelled the likelihood of transfusion, adjusted for baseline covariates. Receiver operating characteristic plots were generated to determine which Hgb threshold best predicted transfusion. Our results informed a quality-improvement initiative involving revised preoperative clinical pathway. Results We included 13,113 patients. A 10 g/L lower Hgb corresponded to 2.81 (95%CI: 2.43–3.25; p Conclusions Our results demonstrate that, at our center, a preoperative Hgb ≤115 g/L distinguishes between joint arthroplasty patients who require transfusion from those who do not. Patient-guided pretransfusion testing may streamline joint arthroplasty program efficiency.
Databáze: OpenAIRE