Studying Hedgehog Signaling During Mouse Neural Tube Development

Autor:	Bandarigoda N. Somatilaka, Saikat Mukhopadhyay, Sandii Constable, Kevin White
Rok vydání:	2021
Předmět:	medicine.anatomical_structure Cilium Neural tube medicine Progenitor cell Biology Hedgehog Transcription factor Immunostaining Hedgehog signaling pathway Progenitor Cell biology
Zdroj:	Hedgehog Signaling ISBN: 9781071617007
DOI:	10.1007/978-1-0716-1701-4_6
Popis:	The identity of ventral neural progenitors in the neural tube is largely dependent on Hedgehog (Hh) signaling. Variations in staining patterns are excellent indicators of aberrant Hh signaling. Here we describe the basic protocol to stain for progenitor populations based on transcription factor expression. We also provide an overview of ciliary and centrosomal staining in the neural tube.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::cec50750cb960ca7d719b7ef29d6e29f https://doi.org/10.1007/978-1-0716-1701-4_6 Zobrazit plný text záznamu