ChemInform Abstract: Synthesis and Biological Evaluation of 4-Deacetoxypaclitaxel

Autor: Ashok G. Chaudhary, David G. I. Kingston, Ernest Hamel, Mahendra D. Chordia, Y. Q. Jiang
Rok vydání: 2010
Předmět:
Zdroj: ChemInform. 26
ISSN: 0931-7597
DOI: 10.1002/chin.199507206
Popis: 4-Deacetoxypaclitaxel ( 9 ) has been prepared in seven steps from paclitaxel (Taxol ® ). It is significantly less active than paclitaxel in tubulin-assembly and cytotoxicity bioassays.
Databáze: OpenAIRE