ChemInform Abstract: Synthesis and Biological Evaluation of 4-Deacetoxypaclitaxel
Autor: | Ashok G. Chaudhary, David G. I. Kingston, Ernest Hamel, Mahendra D. Chordia, Y. Q. Jiang |
---|---|
Rok vydání: | 2010 |
Předmět: | |
Zdroj: | ChemInform. 26 |
ISSN: | 0931-7597 |
DOI: | 10.1002/chin.199507206 |
Popis: | 4-Deacetoxypaclitaxel ( 9 ) has been prepared in seven steps from paclitaxel (Taxol ® ). It is significantly less active than paclitaxel in tubulin-assembly and cytotoxicity bioassays. |
Databáze: | OpenAIRE |
Externí odkaz: |