| Popis: |
As reviewed above, there is abundant evidence implicating autonomic dysfunction or cytokine excess in diseases with inflammatory pathology such as sepsis, Crohn’s disease, and rheumatoid arthritis. The identification of a vagus nerve mechanism that regulates cytokine activity and immune cell activation now suggests that some neurological or nervous system disorders may in fact manifest as inflammatory conditions, and thus alter the optimal treatment. The ability to rationally modulate vagus nerve activity through biofeedback techniques now makes it plausible to consider how to study the regulation of cytokine synthesis in volunteer subjects and patients under varying states of vagus nerve activity. |
