Comparison between exercise myocardial perfusion and wall motion using 201 T1 and 191 Irm simultaneously
| Autor: | P. R. FRANKEN, A. A. DOBBELEIR, H. R. HAM, R. RANQUIN, S. LIEBER, F. VAN DEN BRANDEN, P. VAN DEN HEUVEL, C. BRIHAYE, M. GUILLAUME, F. F. KNAPP, J. VANDEVIVERE |
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| Rok vydání: | 1991 |
| Předmět: |
medicine.medical_specialty
medicine.diagnostic_test business.industry medicine.medical_treatment chemistry.chemical_element General Medicine medicine.disease Revascularization Coronary artery disease Restenosis chemistry Internal medicine Cardiology Medicine Thallium Radiology Nuclear Medicine and imaging In patient Angiocardiography Radiology Wall motion business Perfusion |
| Zdroj: | Nuclear Medicine Communications. 12:473-484 |
| ISSN: | 0143-3636 |
| DOI: | 10.1097/00006231-199106000-00002 |
| Popis: | By exploiting the ultrashort half-life 191Irm as tracer for left ventricular first-pass angiocardiography and 201Tl as myocardial perfusion agent, direct comparison between myocardial perfusion and regional wall motion was obtained during the same exercise stress test in patients with non-significant coronary artery disease, in patients with recent myocardial infarction, and in patients six weeks after successful percutaneous transluminal coronary angioplasty (PTCA). A good agreement between regional myocardial perfusion and regional wall motion was observed in patients with non-significant coronary artery disease and in most patients with recent myocardial infarction. In contrast, discrepancies occurred at maximal exercise in patients studied six weeks after successful PTCA: only 38% of the patients with no evidence of restenosis and with a completely normal myocardial perfusion scintigraphy had a normal regional wall motion at maximal exercise stress. According to these results, a normal uptake of 201Tl six weeks after PTCA would mean that the circulation has been successfully reestablished but without predicting the functional capacities of the myocardial cells which remain altered at least six weeks after the revascularization procedure in about two-thirds of the patients. We conclude that 191Irm in combination with 201Tl offers the opportunity of performing myocardial perfusion and wall motion studies simultaneously both at rest and during exercise. |
| Databáze: | OpenAIRE |
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