Prostanoids: Synthesis of Enantiomers of 15-Deoxy-16-hydroxy-16-methylprostaglandin E1

Autor: Miroslav Terinek, Václav Kozmík, Jaroslav Paleček
Rok vydání: 1997
Předmět:
Zdroj: Collection of Czechoslovak Chemical Communications. 62:1325-1341
ISSN: 1212-6950
0010-0765
DOI: 10.1135/cccc19971325
Popis: Four optically pure isomers of methyl 11,16-dihydroxy-16-methyl-9-oxoprost-13-enoate (1a-1d) were synthesized using an approach reverse to the classical Corey procedure, the key intermediates being the easily accessible (-)- and (+)-enantiomers of the Corey lactone, 2a and 2b.
Databáze: OpenAIRE