Prostanoids: Synthesis of Enantiomers of 15-Deoxy-16-hydroxy-16-methylprostaglandin E1
Autor: | Miroslav Terinek, Václav Kozmík, Jaroslav Paleček |
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Rok vydání: | 1997 |
Předmět: | |
Zdroj: | Collection of Czechoslovak Chemical Communications. 62:1325-1341 |
ISSN: | 1212-6950 0010-0765 |
DOI: | 10.1135/cccc19971325 |
Popis: | Four optically pure isomers of methyl 11,16-dihydroxy-16-methyl-9-oxoprost-13-enoate (1a-1d) were synthesized using an approach reverse to the classical Corey procedure, the key intermediates being the easily accessible (-)- and (+)-enantiomers of the Corey lactone, 2a and 2b. |
Databáze: | OpenAIRE |
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