Austrian syndrome followed by severe cutaneous adverse reactions in a HIV patient
| Autor: | Amara Sarwal, Venkata Sireesha Chemarthi, Karen Hennessey, Chia-Yu Chiu |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Microbiology (medical) medicine.medical_specialty Septic shock business.industry Austrian syndrome 030106 microbiology medicine.disease Dermatology Toxic epidermal necrolysis 03 medical and health sciences Pneumonia 0302 clinical medicine Infectious Diseases Bacteremia medicine Endocarditis Eosinophilia Pharmacology (medical) 030212 general & internal medicine medicine.symptom business Meningitis |
| Zdroj: | Journal of Infection and Chemotherapy. 27:526-529 |
| ISSN: | 1341-321X |
| DOI: | 10.1016/j.jiac.2020.10.003 |
| Popis: | Invasive pneumococcal infection, defined as the combination of pneumonia with endocarditis and meningitis, was described as Austrian syndrome in the 1800s. We report the case of a 63-year-old woman with underlying human immunodeficiency virus who presented with fever and altered mental status. Subsequent workup supported a diagnosis of Austrian syndrome. During the 5-week course of ceftriaxone treatment, she developed fever, pruritus and follicular accentuation throughout the body. Labs were significant for eosinophilia, which along with systemic symptoms, supported the diagnosis of a drug reaction. Coagulase negative staphylococcus bacteremia was discovered when the patient developed septic shock. Subsequently, diffuse desquamative eruption with rapidly progressing sloughing appeared and biopsy proved toxic epidermal necrolysis. Patient eventually succumbed to multiorgan failure. |
| Databáze: | OpenAIRE |
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