Efficient Synthesis of Unsymmetrical Heteroaryl Ethers by a Transition Metal-Free CO Cross-Coupling Reaction of Activated and Unactivated Heteroaryl Chlorides with Alcohols and Phenols

Autor:	Zhongxiang Lu, Yu Wang, Qing Xu, Liu Quan, Wenfei Ren, Kaibo Shen
Rok vydání:	2013
Předmět:	chemistry.chemical_classification Reaction conditions chemistry.chemical_compound Primary (chemistry) Transition metal chemistry Aryl General Chemistry Phenols Combinatorial chemistry Coupling reaction Alkyl
Zdroj:	Chinese Journal of Chemistry. 31:764-772
ISSN:	1001-604X
DOI:	10.1002/cjoc.201300120
Popis:	By optimizing the reaction conditions via a careful screening of the bases and solvents, we developed an efficient transition metal-free method for CO cross-coupling of activated and unactivated heteroaryl chlorides with primary and secondary alcohols and phenols, providing a simple, efficient, and practical method for synthesis of the useful unsymmetrical heteroaryl alkyl and heteroaryl aryl ethers.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::cb8ce4d5bfca9e2b8225b194d07917f1 https://doi.org/10.1002/cjoc.201300120 Zobrazit plný text záznamu Plný text ve formátu PDF