| Autor: |
Elisa Messina, Alessandro Giacomello, Andrea Modesti, C. P. Quaratino, F. Savini, Fortunata Vasaturo, C. Rucci, Susanna Scarpa |
| Rok vydání: |
1998 |
| Předmět: |
|
| Zdroj: |
Advances in Experimental Medicine and Biology ISBN: 9781461374565 |
| Popis: |
Purpose of the present study was to investigate in human neuroblastoma (NB) cell lines the effects of GTP depletion induced by mycophenolic acid (MPA) (the most specific IMP dehydrogenase inhibitor): 1. on biopterin biosynthesis, using cytotoxic drug concentrations in short-term experiments; 2. on cellular differentiation and extracellular matrix remodelling, using drug concentrations below those inducing apoptosis.1 |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
