Official Positions for FRAX® Clinical Regarding Smoking

Autor: David Kendler, Jan Stepan, Michael McClung, Alireza Moayyeri, Robert Daniel Blank
Rok vydání: 2011
Předmět:
Zdroj: Journal of Clinical Densitometry. 14:190-193
ISSN: 1094-6950
DOI: 10.1016/j.jocd.2011.05.011
Popis: The worldwide prevalence of smoking has been estimated at about 50% in men, and 10% in women, with larger variations among different populations studied. Smoking has been shown to affect many organ systems resulting in severe morbidity and increased mortality. In addition, smoking has been identified as a predictor of ten-year fracture risk in men and women, largely independent of an individual's bone mineral density. This finding has eventually lead to incorporation of this risk factor into FRAX®, an algorithm that has been developed to calculate an individual's ten-year fracture risk. However, only little, or conflicting data is available on a possible association between smoking dose, duration, length of time after cessation, type of tobacco and fracture risk, limiting this risk factor's applicability in the context of FRAX®.
Databáze: OpenAIRE