Site-Related Difference in the Prevalence of Mitral Valve Prolapse. Relation to the Prevalence and Severity of Mitral Regurgitation

Autor: Shigemichi Tanaka, Naoko Takahashi, Shuji Yonekura, Akiyoshi Hashimoto, Osamu Iimura, Nobuichi Hikita, Kazuaki Shimamoto, Keiko Sudoh, Toshiaki Kijima, Hironori Murakami, Kazuhiko Nagao
Rok vydání: 1991
Předmět:
Zdroj: Japanese Heart Journal. 32:785-798
ISSN: 1348-673X
0021-4868
DOI: 10.1536/ihj.32.785
Popis: In this study, 431 consecutive patients with mitral valve prolapse (MVP) diagnosed by two-dimensional echocardiography were employed to further investigate the site-related difference in the prevalence of MVP. Following echocardiographic determination of the site and severity of MVP, a pulsed-Doppler technique was further performed to assess the existence and severity of mitral regurgitation (MR) in all patients. These patients were then classified by age in 10-year groups with patients older than 60 years being enrolled in one group. The younger groups accounted for a large number of the patients with MVP in our study, with the number of patients being reduced with age. In addition, female patients tended to predominate up until the 50s, but not in the 50 and older groups. The prevalence of MVP at the centro-medial site of the anterior mitral leaflet (AML) predominated in all age groups, gradually decreasing with age, except for a peak in the 40s, before continuing to decline in the 50 and older groups. On the other hand, the prevalence of MVP at the lateral site of the AML and at the posterior mitral leaflet (PML) increased with age. In the 50 and older age groups, the prevalence of MVP at these sites increased steeply with age. However, the prevalence of MVP at both the lateral site of the AML and PML did not significantly increase with age. The trend shown above was not significantly different for gender. The number of patients with MR increased with age independent of the site of MVP. However, the prevalence and severity of MR associated with MVP at the lateral site of the AML and/or at the PML were significantly greater than at the other sites up until the 50s (p
Databáze: OpenAIRE