A gold nanoparticles - Graphene based electrochemical sensor for sensitive determination of nitrazepam
| Autor: | Florin Banica, Traian Costea, Liviu Moldovan, Luminiţa Fritea, Simona Cavalu, Ciprian Iovan |
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| Rok vydání: | 2018 |
| Předmět: |
Nanostructure
Chemistry Scanning electron microscope Graphene General Chemical Engineering 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences Analytical Chemistry Electrochemical gas sensor law.invention Nanomaterials Chemical engineering law Colloidal gold Electrochemistry Fourier transform infrared spectroscopy 0210 nano-technology Spectroscopy |
| Zdroj: | Journal of Electroanalytical Chemistry. :63-71 |
| ISSN: | 1572-6657 |
| DOI: | 10.1016/j.jelechem.2018.10.015 |
| Popis: | A new nanoplatform based on reduced graphene oxide decorated with electrochemically generated gold nanoparticles was developed for sensitive and selective determination of nitrazepam. This nanostructure was characterized by Fourier transform infrared spectroscopy, atomic force microscopy, scanning electron microscopy coupled with energy dispersive X-ray spectroscopy and electrochemical methods. The synergic effect of the two nanomaterials gives an electrode platform with a high surface area, good conductivity and excellent catalytic properties. The sensor exhibited a wide linear range (0.5 μM–400 μM), low limit of detection (0.166 μM), excellent sensitivity, good selectivity, and high stability for nitrazepam determination in serum and a pharmaceutical formulation with excellent recovery rates (99%–102.4%). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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