| Autor: |
Alberto Abrate, Cristina Scalici Gesolfo, Alchiede Simonato |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Practical Medical Oncology Textbook ISBN: 9783030560508 |
| DOI: |
10.1007/978-3-030-56051-5_50 |
| Popis: |
Penile carcinoma is a rare and aggressive disease. Its incidence is related with age over 60 and presence of comorbidities such as HPV infection. The higher incidence rate is reached in developing countries. Penile carcinoma is generally a squamous cell carcinoma and it is frequently foregone by a premalignant lesion. Because of its short time to progression, an early detection is mandatory. Good physical examination is the first step toward a correct diagnosis and staging. CT scan and chest X-ray are useful for nodal stage while US and MRI can provide a preoperative assessment of local invasion. Surgical approach depends on invasion and nodal involvement, varying from a local laser ablation to a radical penectomy associated with an inguinal lymphadenectomy. A correct management of nodal disease is crucial to control the penile carcinoma and reduce comorbidities. Systemic chemotherapy could be offered as neoadjuvant treatment in patients with non-resectable nodes and as adjuvant treatment in patients with locally advanced or systemic disease. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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