Maternal hemodynamic changes in gestational diabetes: a prospective case–control study
| Autor: | Serena Ottanelli, Herbert Valensise, I. Pisani, Felice Petraglia, Serena Simeone, Marianna Pina Rambaldi, Silvia Vannuccini, Caterina Serena, Federica Lisi, Sara Clemenza, Federico Mecacci |
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| Rok vydání: | 2021 |
| Předmět: |
Pregnancy
medicine.medical_specialty endocrine system diseases business.industry Obstetrics Case-control study Cardiac index nutritional and metabolic diseases Obstetrics and Gynecology Gestational age Hemodynamics General Medicine Stroke volume medicine.disease female genital diseases and pregnancy complications Gestational diabetes medicine.anatomical_structure medicine Vascular resistance business |
| Zdroj: | Archives of Gynecology and Obstetrics. 306:357-363 |
| ISSN: | 1432-0711 |
| DOI: | 10.1007/s00404-021-06288-0 |
| Popis: | The aim of the study is to compare maternal hemodynamic adaptations in gestational diabetes (GDM) versus healthy pregnancies. A prospective case–control study was conducted, comparing 69 singleton pregnancies with GDM and 128 controls, recruited between September 2018 and April 2019 in Maternal–Fetal Medicine Unit, Careggi University Hospital, Florence, Italy. Hemodynamic assessment by UltraSonic Cardiac Output Monitor (USCOM) was performed in both groups in four gestational age intervals: 17–20 weeks (only in early GDM cases), 26–30 weeks, 32–35 weeks and 36–39 weeks. We evaluated six hemodynamic parameters comparing GDM cases versus controls: cardiac output (CO), cardiac index (CI), stroke volume (SV), total vascular resistance (TVR), inotropy index (INO) and potential to kinetic energy ratio (PKR). GDM group had significantly lower values of CO and SV than controls from the early third trimester (26–30 weeks) until term (p |
| Databáze: | OpenAIRE |
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