ChemInform Abstract: One-Step Synthesis of 4-Alkyl-3-aryl-2,6-dicyanoanilines and Their Use in the Synthesis of Highly Functionalized 2,3,5,6,7- and 2,3,4,5,7-Substituted Indoles

Autor:	Subhash P. Chavan, Jaisingh M. Divse, Hanumant B. Borate, Ananada S. Kudale, Dattatry S. Bhosale, Sangmeshwer P. Sawargave, Jaydeep V. Deore
Rok vydání:	2012
Předmět:	chemistry.chemical_classification Ethyl bromoacetate chemistry.chemical_compound chemistry Morpholine Aryl Organic chemistry Molecule One-Step General Medicine Aldehyde Alkyl Malononitrile
Zdroj:	ChemInform. 43
ISSN:	0931-7597
DOI:	10.1002/chin.201205124
Popis:	A three-component, one-step method for the synthesis of 4-alkyl-3-aryl-2,6-dicyanoanilines involving reaction of alkyl aldehyde, malononitrile and aryl aldehyde in presence of morpholine is reported. Highly functionalized 2,3,5,6,7- and 2,3,4,5,7-substituted indoles were prepared from these dicyanoanilines by reaction with ethyl bromoacetate. These substituted dicyanoanilines and indoles have a potential to be converted into various other compounds taking advantage of various functional groups present in these molecules.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c491b3789cd4435bb9cc48d67b08be1f https://doi.org/10.1002/chin.201205124 Zobrazit plný text záznamu Plný text