ORP4L couples IP 3 to ITPR1 in control of endoplasmic reticulum calcium release
| Autor: | Guoping Pan, Weize Lin, Xiuye Cao, Vesa M. Olkkonen, Meng-Yang Xu, Daoguang Yan, Peipei Xie, Shiqian Li, Wenbin Zhong, Jun Xu, Dan Li, Yong Tang, Jianuo Chen |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Scaffold protein Bioenergetics Endoplasmic reticulum chemistry.chemical_element Calcium Biochemistry Cell biology 03 medical and health sciences chemistry.chemical_compound 030104 developmental biology 0302 clinical medicine Membrane chemistry Genetics Inositol Molecular Biology 030217 neurology & neurosurgery Ca2 signaling Biotechnology |
| Zdroj: | The FASEB Journal. 33:13852-13865 |
| ISSN: | 1530-6860 0892-6638 |
| DOI: | 10.1096/fj.201900933rr |
| Popis: | Oxysterol-binding protein–related protein (ORP) 4L acts as a scaffold protein assembling CD3-e, G-αq/11, and PLC-β3 into a complex at the plasma membrane that mediates inositol (1,4,5)-trisphosphat... |
| Databáze: | OpenAIRE |
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