| Autor: |
Ioanna Theodorou, Nam Nguyen Quang, Benoît Lelandais, Karine Gombert, Frédéric Ducongé, Benoit Thézé |
| Rok vydání: |
2016 |
| Předmět: |
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| Zdroj: |
Methods in Molecular Biology ISBN: 9781493931965 |
| DOI: |
10.1007/978-1-4939-3197-2_11 |
| Popis: |
Fluorescence imaging techniques could be used in different ways to study the interaction of aptamers with biological systems from cell culture to animal models. Here, we present the methods developed in our laboratory for fluorescently labeled aptamers, study their internalization inside living cells using time-lapse microscopy, and monitor their biodistribution in mice bearing subcutaneous xenograft tumors using planar fluorescence imaging and fluorescence diffuse optical tomography (fDOT). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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