| Autor: |
Jui-hung Tsai, I-Ting Liu, Pei-Fang Su, Ying-Tzu Huang, Ge-Lin Chiu, Yu-Yeh Chen, Wei-Shu Lai, Peng-Chan Lin |
| Rok vydání: |
2021 |
| DOI: |
10.21203/rs.3.rs-564703/v1 |
| Popis: |
PurposeLimited efficacy has been observed when using morphine to treat neuropathic pain. Lidocaine patches reduce neuropathic pain in post-herpetic neuralgia, but their benefits for cancer-related neuropathic pain remain unclear. This study aimed to demonstrate a useful treatment for cancer-related neuropathic pain. The primary endpoint was pain intensity evaluated by the visual analog scale (VAS). The secondary endpoints were the pain relief score and the quality of analgesic treatment. MethodsWe assessed the efficacy and safety of lidocaine patches in patients experiencing neuropathic cancer pain. Terminal cancer patients with opioid treatment resistance participated in the 3-day study. ResultsThe results showed a statistically significant difference in the median VAS over three days (Kruskal-Wallis test, P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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