Palladium-Catalyzed Alkylation-Alkenylation Reactions: Rapid Access to Tricyclic Mescaline Analogues

Autor:	Dino Alberico, Mark Lautens
Rok vydání:	2006
Předmět:	chemistry.chemical_classification Aryl Organic Chemistry Iodide chemistry.chemical_element Alkylation Medicinal chemistry Catalysis chemistry.chemical_compound chemistry Heck reaction Alkyl Tricyclic Palladium
Zdroj:	Synlett. 2006:2969-2972
ISSN:	1437-2096 0936-5214
Popis:	A norbomene-mediated palladium-catalyzed sequence is described in which two alkyl-aryl bonds and one alkenyl-aryl bond are formed in one pot. A variety of symmetrical and unsymmetrical tricyclic heterocycles were synthesized in good yields from a Heck acceptor and an aryl iodide containing two tethered alkyl bromides. This methodology was applied to the synthesis of a tricyclic mescaline analogue.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c261aa9f9f914bb1bca62d2bbbc7656b https://doi.org/10.1055/s-2006-941583 Zobrazit plný text záznamu