Anti-diabetic activity of diphenhydramine in diabetic rats
| Autor: | RM Noah, Kaswandi Md Ambia, Nurul Ain, Pang Jyh Chayng |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Diphenhydramine hydrochloride Diabetic rat business.industry Insulin medicine.medical_treatment Diphenhydramine Group ii Streptozotocin Every Three Days Glibenclamide Endocrinology Internal medicine medicine General Pharmacology Toxicology and Pharmaceutics business medicine.drug |
| Zdroj: | International Journal of Research in Pharmaceutical Sciences. 11:5067-5070 |
| ISSN: | 0975-7538 |
| DOI: | 10.26452/ijrps.v11i4.3102 |
| Popis: | The purpose of this project is to study the anti-diabetic effect of on a diabetic rat model. A total of Twenty male Sprague rats were used and it randomly distributed into four groups which are Group I: , Group II: negative control, Group III: and Group IV: and . In diabetic model were induced with via injection at the dosage of 65mg/kg. and FBG (Fasting Blood Glucose) level of diabetic rats were assessed every three days. Blood was collected via cardiac puncture at day 21 after the induction of treatment. Insulin level of the rats was assessed with the Mercodia Rat Insulin ELISA kit. FBG level of group I (12.16 ±3.96, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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