A ConvenientN-Protection of Pyroglutamate Derivatives

Autor: Yasuo Kikugawa, Takeshi Sakamoto, Miyako Kato, Hao Li
Rok vydání: 1995
Předmět:
Zdroj: Synthetic Communications. 25:4045-4052
ISSN: 1532-2432
0039-7911
DOI: 10.1080/00397919508011481
Popis: Esters of pyroglutamic acid were N-protected by conventional protective groups (Z. Boc, and COOMe) in high yield, without racemization, using LiHMDS in THF at - 78 °C and ZCl, Boc2O, and ClCOOMe, respectively.
Databáze: OpenAIRE