The Quality and Management of Penicillin Allergy Labels in Pediatric Primary Care

Autor: Margaret G. Taylor, Torsten Joerger, Sara Anvari, Yun Li, Jeffrey S. Gerber, Debra L. Palazzi
Rok vydání: 2023
Předmět:
Zdroj: Pediatrics. 151
ISSN: 1098-4275
0031-4005
DOI: 10.1542/peds.2022-059309
Popis: BACKGROUND AND OBJECTIVESPenicillin allergy labels are the most common drug allergy label. The objective of this study was to describe the quality and management of penicillin allergy labels in the pediatric primary care setting.METHODSRetrospective chart review of 500 of 18 015 children with penicillin allergy labels born from January 1, 2010 to June 30, 2020 randomly selected from an outpatient birth cohort from Texas Children’s Pediatrics and Children’s Hospital of Philadelphia networks. Penicillin allergy risk classification (“not allergy,” “low risk,” “moderate or high risk,” “severe risk,” “unable to classify”) was determined based on documentation within (1) the allergy tab and (2) electronic healthcare notes. Outcomes of allergy referrals and penicillin re-exposure were noted.RESULTSHalf of penicillin allergy labels were “unable to classify” based on allergy tab documentation. Risk classification agreement between allergy tabs and healthcare notes was fair (Cohen’s ĸ = 0.35 ± 0.02). Primary care physicians referred 84 of 500 (16.8%) children to an allergist, but only 54 (10.8%) were seen in allergy clinic. All children who were challenged (25 of 25) passed skin testing. Removal of allergy labels was uncommon (69 of 500, 13.8%) but occurred more often following allergy appointments (26 of 54, 48%) than not (43 of 446, 9.6%, P < .001). Children delabeled by primary care physicians were as likely to tolerate subsequent penicillin-class antibiotics as those delabeled by an allergist (94% vs 93%, P = .87).CONCLUSIONSPenicillin allergy documentation within the allergy tab was uninformative, and children were infrequently referred to allergists. Future quality improvement studies should improve penicillin allergy documentation and expand access to allergy services.
Databáze: OpenAIRE
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