How miRNA Structure of Animals Influences Their Biogenesis

Autor:	P. S. Vorozheykin, I. I. Titov
Rok vydání:	2020
Předmět:	0106 biological sciences 0303 health sciences Computational biology Biology 01 natural sciences Human genetics 03 medical and health sciences Epitranscriptomics Gene expression microRNA Genetics Genetic variability Gene Biogenesis 030304 developmental biology 010606 plant biology & botany
Zdroj:	Russian Journal of Genetics. 56:17-29
ISSN:	1608-3369 1022-7954
DOI:	10.1134/s1022795420010135
Popis:	MicroRNAs are small noncoding RNAs that are involved in the post-transcriptional regulation of the gene expression in various organisms. This article reviews recent advances in understanding the role of the primary and secondary structures of animal miRNA precursors through the biogenesis stages and the miRNA maturation steps. Also, we describe the effects of genetic variability and heterogeneity of miRNA ends, which play an important role in epitranscriptomics as well as annotation errors in the miRNA databases.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::c009058e91274cd5db8b6fdcb561b788 https://doi.org/10.1134/s1022795420010135 Zobrazit plný text záznamu Full text from SpringerLink