Treatment adherence and unmet needs at hospital pharmacy for the care of Spanish patients with multiple sclerosis

Autor: Paula Pérez-Puente, Aitziber Illaro-Uranga, Luis Margusino-Framiñán, María Ángeles Porta-Sánchez, Jesús Mayorga-Pérez, Patricia Sanmartín-Fenollera, Inmaculada Ramírez-Alapont, Laura Lorente-Fernández, Emilio Monte-Boquet, Javier García-Fernández, Miguel Ángel Conesa-Muñoz, Ana García-Monsalve, Isabel Moya-Carmona, Ignacio Cardona-Pascual, Elena Victoria Tortajada-Esteban, José Ramón Vizoso-Hermida, Sheila Mora-García, María Fernández-Pacheco, María Olatz Ibarra-Barrueta
Rok vydání: 2012
Předmět:
Zdroj: European Journal of Hospital Pharmacy. 20:20-25
ISSN: 2047-9964
2047-9956
DOI: 10.1136/ejhpharm-2012-000183
Popis: Objective To assess unmet needs at hospital pharmacies and treatment adherence of patients with multiple sclerosis (MS) treated with disease-modifying therapies (DMTs). Methods A non-interventional and multicentre study involving 24 pharmacies that included 237 patients with relapsing-remitting MS (RRMS) or secondary progressive MS (SPMS) treated with DMTs. Pharmacists completed a questionnaire on management and needs. Adherence was assessed using the Morisky-Green test. Results The mean age of patients was 40.1±9.4 years (65.8% women). The average time from diagnosis was 7.5±5.6 years, 95.4% had RRMS and 61.2% had no relapses during the last year. Most patients (62.4%) had Expanded Disability Status Scale grade 0–2.5. Overall adherence was 77.1%. Treatment adherence was significantly higher among patients with no relapses (82.9% vs 67.4%, p Conclusions It is necessary to improve educational materials and operational protocols regarding workload at hospital pharmacies to provide adequate follow-up and to ensure adherence by Spanish patients with MS.
Databáze: OpenAIRE