Analgesic, Anti-Inflammatory and Antipyretic Potential of the Stem Bark Extract of Stachytarpheta indica

Autor: P. M. Udia, A. D. Essien, Essien David-Oku, KC Chilaka, E.C. Asika, G.C. Akuodor, S.K. Nwadum
Rok vydání: 2015
Předmět:
Zdroj: British Journal of Pharmacology and Toxicology. 6:16-21
ISSN: 2044-2467
2044-2459
DOI: 10.19026/bjpt.6.5187
Popis: Aim of study: Stachytarpheta indica is used as herbal remedy for pains in Nigeria. Methods: To validate this claim, the analgesic, anti-inflammatory and antipyretic effects of the stem bark extract were examined in mice and rats by using acetic acid-induced writhing, tail immersion, xylene and egg albumin-induced paw oedema. While yeast and amphetamine induced pyrexia were used to study antipyretic activity in rats. LD50 of the stem bark extract was carried out to determine its safety. Results: The methanol stem bark extract of Stachytarpheta indica showed significant (p
Databáze: OpenAIRE
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