A heavy-ion production channel of 149Tb via 63Cu bombardment of 89Y

Autor: Graham F. Peaslee, Samuel J. Ferran, Jonathan W. Engle, Sherry Yennello, Kendall E. Barrett, Suzanne E. Lapi, John Wilkinson, Lauren A. McIntosh, Sean R. McGuinness, Mallory A. McCarthy
Rok vydání: 2021
Předmět:
Zdroj: Applied Radiation and Isotopes. 178:109935
ISSN: 0969-8043
DOI: 10.1016/j.apradiso.2021.109935
Popis: The radionuclide 149Tb (t1/2 = 4.1 h) is a potential theranostic isotope which can simultaneously be used for targeted-alpha-particle therapy and positron-emission tomography. Feasibility experiments were performed to test a near-symmetric heavy-ion reaction of 63Cu bombardment on monoisotopic 89Y. The indirect reaction was studied to avoid isomer production. Offline gamma spectroscopy was used to quantify thick-target physical yields and experimental results show modest agreement to the fusion-evaporation code PACE4. A near-symmetric fission yield was also observed.
Databáze: OpenAIRE