Abstract WMP67: Cerebral Collateral Flow State Correlates With Stroke Severity And Functional Outcomes

Autor: Smit Shah, Karly Pikel, Kathryn Thornton, Gowri Peethambar, Nishanth Kodumuri, Forrest Lowe, Ravish A Kothari, Line Abdul Rahman, yedatore s venkatesh, Souvik Sen
Rok vydání: 2023
Předmět:
Zdroj: Stroke. 54
ISSN: 1524-4628
0039-2499
DOI: 10.1161/str.54.suppl_1.wmp67
Popis: Introduction: Hypoperfusion index ratio (HIR) measured by computerized tomography perfusion (CTP) has been shown to predict collateral flow state in acute ischemic stroke (AIS). Low HIR ( Hypothesis: Good collateral flow state correlates with lower stroke severity and better clinical outcome at discharge. Methods: Data from AIS patients who underwent CTP during initial stroke evaluation were linked with Get With the Guideline database in a comprehensive stroke center between 2018 and 2020. Patients with good collateral flow (HIR Results: CT perfusion data was obtained in 1442 patients, after excluding patients who underwent thrombectomy and all non-vascular etiologies of stroke like presentation, there was 890 patients (age 68±14, 52% male, 50% white, 50% black/others), of who 756 (85%) demonstrated good collateral flow and 134 (15%) showed poor collateral flow. Those with good collateral flow were younger (68±14 vs. 70±15, p=0.07) and lower median NIHSS (6 IQR 3-10 vs. 13 IQR 6-18, p Conclusions: In patients presenting with AIS, good collateral flow state was associated with lower stroke severity. It was independently associated with good outcome after adjustment for several comorbidities. Based on our study results, CT perfusion imaging may have utility in predicting stroke severity and discharge outcome.
Databáze: OpenAIRE